URGENT: COST action - Seeking implant company to transform cell adhesion complexes to therapeutic targets

Center name Тестовый центр
Summary A UK university is part of a COST (European Cooperation in Science and Technology) Action consortium aimed at identifying crucial components of cell adhesion complexes (CACs) serving as novel therapeutic targets for different diseases. The consortium are seeking a European company working with implantable devices, nanopatterning or biotherapeutics to join this under a research cooperation agreement.
Description of the offer CACs consist of clusters of transmembrane receptors that bind to extracellular matrix (ECM) components and neighbouring cells outside the cell while anchoring intracellular cytoskeletal structural proteins and signal transduction molecules on the inside. CACs are dynamic structures that sense physical and biochemical cues from the environment and transmit such information to the cell interior to regulate cell shape and function. In normal tissue, the compositions of CACs are tightly regulated but changes in the expression or activity of many of their components is associated with a variety of human diseases. Interventions targeting CACs components represent a potentially important therapeutic approach. To reach the full societal and economical potential of therapeutic strategies targeting CACs, the diversity of excellent science in this field must become more integrated and coupled to clinical application. COST is the longest-running European framework supporting trans-national cooperation among researchers, engineers and scholars across Europe. COST Actions allow European researchers to jointly develop their own ideas in any science and technology field. COST funds pan-European, bottom-up networks of scientists and researchers across all science and technology fields. These networks, called 'COST Actions', promote international coordination of nationally-funded research. COST is supported by the EU Framework Programme Horizon 2020. This consortium and COST action (known as CellAC) aims to establish a network to unify the complementary expertises of world-class CACs fundamental researchers and clinicians in Europe. The group already consists of 53 partners, including German, Swiss, Swedish, Dutch, Cypriot, UK, Italian, American, Greek, Austrian, Norwegian, Czech, French, Israeli, and Crotian universities, a German company and a Spanish, Greek, and Scottish research institute. They are seeking an additional industry partner from within the EU to join the bid as part of a research cooperation agreement, that currently has experience working in one or more of the following areas: - Nanopatterning - Implantable devices - Diagnostics - Drug discovery - Imaging development - Biotherapeutics It is anticipated that the company will be able to contribute towards a greater understanding of the function of CACs proteins that will enable identification of key therapeutic attack-points in CACs. The deadline for the bid is 17 November 2016 and the deadline for expressions of interest in this call is 15 November 2016.
Technological Keywords 06001002 Clinical Research, Trials
06001003 Cytology, Cancerology, Oncology
06001012 Medical Research
06001013 Medical Technology / Biomedical Engineering
06001024 Medical Biomaterials
Market Keywords 04006 Cellular and Molecular Biology
04007 Enzymology/Protein Engineering/Fermentation
04010 Microbiology
04015 Gene Expression, Proteome Research
05002 Medical imaging
Type of Partnership Required Research cooperation agreement
Partner's sphere of activity Type: Industry Activity: Biomedical devices, implants, biotherapeutics Specific role of partner in this project: To contribute expertise, tools and devices for ongoing testing or trials, medical research. To interact with academic scientists to explore translation of basic research into medical applications.
Date of creation 11/04/2016
Profile type Research Development Request
Profile openness to interact Y
Profile from EEN Y

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